Investigation of the quality of air includes a series of specific emission and immision measurements of pollutants and it is regulated by domestic and foreign laws. The urban traffic is considered one of the emitters of noxious matters in the air. The emission of exhaust gases from the internal combustion engines is the source of numerous pollutants: burned or partially burned hydrocarbon, carbon monoxide, nitrogen oxides, soot, etc. The paper presents a numerical model that enables prevention of carbon monoxide concentration in the air based on air parameters measured through forming algebraic polynomials by the least-squares method. The measurement of parameters was performed in the Republic Institute of Public Health, at the location near the National Theatre in the Mediana Municipality, the City of Niš. The numerical model was realized in the symbolic system of Mathematica. Based on the formed model, numerical results are given related to the monitoring of carbon monoxide in the air caused by the traffic pollution.