Synergistic effect of Fe and Co doped ZnO nanoparticles synthesized using Alpinia galanga  against Candida parasilopsis

Narendhran S

doi:10.62638/ZasMat1131

Authors

Narendhran S Department of Biotechnology, Sri Krishna Arts and Science College, Kuniamuthur, Coimbatore, India Author

DOI:

https://doi.org/10.62638/ZasMat1131

Abstract

In this investigation, nanoparticles such as ZnO, Fe doped ZnO and Co doped ZnO NPs prepared by the co-precipitation method were tested against the pathogenic yeast. The spectroscopic analyses were carried out to identify the morphological and chemical composition of the synthesized nanoparticles. The results of XRD analysis revealed that the synthesized nanoparticles were crystalline in nature with average size ranges between 32 – 34 nm approximately. EDX and SEM analysis were carried out to identify the element composition (Co, Fe and Zn) and spherical shape of nanoparticles. The functional group that is responsible for the capping and stability of nanoparticles was confirmed by FTIR analysis, to compare the antifungal efficiency of ZnO, Fe doped ZnO and Co doped ZnO from the resultant zone of inhibition.

Keywords:

Antifungal activity, Candida parapsilosis, Copper, Iron, Zinc

Supporting Agencies

We thank to the Management of Sri Krishna Arts and Science College, Coimbatore, Tamil Nadu, India for the Seed money grant and providing necessary facilities to carry out this work.

References

E.J.Baron, J.M.Miller (2008) Bacterial and fungal infections among diagnostic laboratory workers: evaluating the risks. Diagn. Micr. Infec. Dis., 60(3), 241–246, https://doi.org/10.1016/j.diagmicrobio.2007.09.016 DOI: https://doi.org/10.1016/j.diagmicrobio.2007.09.016

J.Kaur, C.J.Nobile (2023) Antifungal drug-resistance mechanisms in Candida biofilms. Curr. Opin. Microbiol., 71, 102237, https://doi.org/10. 1016/ j.mib.2022.102237 DOI: https://doi.org/10.1016/j.mib.2022.102237

A.Espinel-Ingroff (2009) Novel antifungal agents, targets or therapeutic strategies for the treatment of invasive fungal diseases: a review of the literature (2005-2009). Rev. Iberoam. Micol., 26(1), 15–22, https://doi.org/10.1016/s1130-1406(09)70004-x DOI: https://doi.org/10.1016/S1130-1406(09)70004-X

A.Chaturvedi, S.Shambhakar (2024) Nanotechnology in Drug Delivery: Overcoming Poor Solubility Challenges through Nanoformulations. Nanomed. J., 14, In Press, https://doi.org/ 10.2174/0124681873276732231207051324 DOI: https://doi.org/10.2174/0124681873276732231207051324

T.A.Wani, G.Suresh (2022) Plant‐Mediated Green Synthesis of Magnetic Spinel Ferrite Nanoparticles: A Sustainable Trend in Nanotechnology. Adv. Sustain. Syst., 6(6),

https://doi.org/10.1002/adsu.202200035 DOI: https://doi.org/10.1002/adsu.202200035

A.Burhan, D.Ratnadewi, A.Setiyono, R.Astuti, A. Umar (2024) Phytochemical Profiling of Hippobroma longiflora Leaf Extract Using LC-MS/MS Analysis and Pharmacological Potential. Egypt. J. Chem., 23, https://doi.org/10.21608/ejchem.2024.242541.8740 DOI: https://doi.org/10.21608/ejchem.2024.242541.8740

S.Chandrasekaran, V.Anbazhagan (2023) Green Synthesis of ZnO and V-Doped ZnO Nanoparticles Using Vinca rosea Plant Leaf for Biomedical Applications. Appl. Biochem. Biotechnol., 196(1), 50–67. https://doi.org/10.1007/s12010-023-04546-2

M.Duan, J.G.Shapter, W.Qi, S.Yang, G.Gao (2018) Recent progress in magnetic nanoparticles: synthesis, properties, and applications. Nanotechnol., 29(45), 452001, https://doi.org/10.1088/1361-6528/aadcec DOI: https://doi.org/10.1088/1361-6528/aadcec

M.S.Nadeem, T.Munawar, F.Mukhtar, M.Naveed, U. Rahman, M.Riaz, F.Iqbal (2021) Enhancement in the photocatalytic and antimicrobial properties of ZnO nanoparticles by structural variations and energy bandgap tuning through Fe and Co co-doping. Ceram. Int., 47(8), 11109–11121, https://doi.org/10.1016/j.ceramint.2020.12.234 DOI: https://doi.org/10.1016/j.ceramint.2020.12.234

R.R.Muthu Chudarkodi, A.Rajalaxshmi (2016) Synthesis, Electrochemical Characterization and Photocatalytic Application of Ceion Doped ZnO nanoparticles using Leaf Extract of SesbaniaGrandiflora by Green Method. Int. J. Sci. Res., 5(3), 1073–1080.

https://doi.org/10.21275/v5i3.15031601 DOI: https://doi.org/10.21275/v5i3.15031601

S.Chandrasekaran, V.Anbazhagan (2023) Green Synthesis of ZnO and V-Doped ZnO Nanoparticles Using Vinca rosea Plant Leaf for Biomedical Applications. Appl. Biochem. Biotechnol., 196(1), 50–67. https://doi.org/10.1007/s12010-023-04546-2 DOI: https://doi.org/10.1007/s12010-023-04546-2

D.Giram, A.Das (2024) Synthesis and characterization of Fe doped ZnO nanoparticles for the photocatalytic degradation of Eriochrome Black-T dye. Indian J. Chem. Techn., In press, https://doi.org/10.56042/ijct.v31i1.4985 DOI: https://doi.org/10.56042/ijct.v31i1.4985

D.Gupta, R.K.Ghanshyam Kotnala, N.S.Negi (2013) Synthesis and characterization of Cu, Fe co-doped ZnO nano-particles synthesized by solution combustion method. AIP Conference Proceedings. https://doi.org/10.1063/1.4810156 DOI: https://doi.org/10.1063/1.4810156

P.Dhiman, R.Rani, M.Singh (2012) Structural and electrical properties of Fe doped ZnO nanoparticles synthesized by solution combustion method. AIP Conference Proceedings.

https://doi.org/10.1063/1.4710002 DOI: https://doi.org/10.1063/1.4710002

P.Dhiman, J.Chand, S.Verma Sarveena, M.Singh (2014) Ni, Fe Co-doped ZnO nanoparticles synthesized by solution combustion method. AIP Conference Proceedings.

https://doi.org/10.1063/1.4872990 DOI: https://doi.org/10.1063/1.4872990

N.Madkhali (2022) Analysis of Structural, Optical, and Magnetic Properties of (Fe,Co) Co-Doped ZnO Nanoparticles Synthesized under UV Light. Condens. Matter., 7(4), 63-71,

https://doi.org/10.3390/condmat7040063 DOI: https://doi.org/10.3390/condmat7040063

P.Malathy, S.Selvarajan (2018) Visible Light Assisted Photocatalytic Activity of Co-doped ZnO, In-Doped ZnO and (Co, In) co- doped ZnO Nanoparticles. Int. J. Nanotechnol. App., 8(1), 1–14, https://doi.org/10.24247/ijnajun20181 DOI: https://doi.org/10.24247/ijnajun20181

T.S.Boopathi, S.Suksom, J.Suriyaprakash, A.H. Hirad, A.A.Alarfaj, I.Thangavelu (2024) Psidium guajava-mediated green synthesis of Fe-doped ZnO and Co-doped ZnO nanoparticles: a comprehensive study on characterization and biological applications. Biopro. Biosyst. Eng., in press, https://doi.org/10.1007/s00449-024-03002-7 DOI: https://doi.org/10.1007/s00449-024-03002-7

W.Kejela Tolossa, P.Taddesse Shibeshi (2022) Structural, optical and enhanced antibacterial activities of ZnO and (Co, Fe) co-doped ZnO nanoparticles by sol-gel combustion method. Chem. Phys. Lett., 795, 139519,

https://doi.org/10.1016/j.cplett.2022.139519 DOI: https://doi.org/10.1016/j.cplett.2022.139519

I.O.Chikezie (2017) Determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) using a novel dilution tube method. Afr. J. Microbiol. Res., 11(23), 977–980, https://doi.org/10.5897/ajmr2017.8545 DOI: https://doi.org/10.5897/AJMR2017.8545

D.Sharma, R.Jha (2017) Transition metal (Co, Mn) co-doped ZnO nanoparticles: Effect on structural and optical properties. J. Alloys Compd., 698, 532–538, https://doi.org/10.1016/j.jallcom.2016.12.227 DOI: https://doi.org/10.1016/j.jallcom.2016.12.227

M.Ram, K.Bala, H.Sharma, A.Kumar, N.S.Negi (2016) Investigation on structural and electrical properties of Fe doped ZnO nanoparticles synthesized by solution combustion method. AIP Conference Proceedings.

https://doi.org/10.1063/1.4946078 DOI: https://doi.org/10.1063/1.4946078

M.D.Sahadat Hossain, S.Ahmed (2023) Easy and green synthesis of TiO2 (Anatase and Rutile): Estimation of crystallite size using Scherrer equation, Williamson-Hall plot, Monshi-Scherrer Model, size-strain plot, Halder- Wagner Model. Results Mater., 20, 100492,

https://doi.org/10.1016/j.rinma.2023.100492 DOI: https://doi.org/10.1016/j.rinma.2023.100492

X.Han, S.Wahl, P.Russo, N.Pinna (2018) Cobalt-Assisted Morphology and Assembly Control of Co-Doped ZnO Nanoparticles. Nanomater., 8(4), 249, https://doi.org/10.3390/nano8040249 DOI: https://doi.org/10.3390/nano8040249

M.Mittal, M.Sharma, O.P.Pandey (2014) UV–Visible light induced photocatalytic studies of Cu doped ZnO nanoparticles prepared by co-precipitation method. J. Sol. Energy., 110, 386–397,

https://doi.org/10.1016/j.solener.2014.09.026 DOI: https://doi.org/10.1016/j.solener.2014.09.026

D.Sharma, R.Jha (2017) Analysis of structural, optical and magnetic properties of Fe/Co co-doped ZnO nanocrystals. Ceram. Int., 43(11), 8488–8496, https://doi.org/10.1016/j.ceramint.2017.03.201 DOI: https://doi.org/10.1016/j.ceramint.2017.03.201

Y.Köseoğlu (2015) Rapid synthesis of room temperature ferromagnetic Fe and Co co-doped ZnO DMS nanoparticles. Ceram. Int., 41(9),11655–11661, https://doi.org/10.1016/j.ceramint.2015.05.127 DOI: https://doi.org/10.1016/j.ceramint.2015.05.127