Synthesis, characterization, chromatographic & antimicrobial studies of transition metal complexes of Cobalt (II) and Iron (III)
DOI:
https://doi.org/10.62638/ZasMat1087Abstract
A metal complex Co(II) and Fe(III) was synthesized by reacting Metal Nitrate with Alprazolam. During this study, The elemental analyses of complexes confines to the stoichiometry of the type [(L) M (NO3)2 ], [(L) M(NO3)3 ] where M= Cobalt(II) & Iron(III) & L= APZ(alprazolam). Alprazolam's IR bands shift to confirm metal ion coordination. Complexes of metal ions were found to be bidentate & tridentate with ‘‘N(1) and N(4)” positions on the ligand. This study examined APZ (alprazolam) & its complexes for their antimicrobial properties against selected bacteria and fungi. Streptomycin & Nyastatin were used as standard drugs for antimicrobial and antifungal studies respectively. These complexes are bioactive. In the present study, metal complexes showed greater activity than drug alprazolam.
Keywords:
metal complexes, infra-red, alprazolam, antimicrobial, bioactiveReferences
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